Antonio Jimenez-Marin, Nele De Bruyn, Jolien Gooijers, Alberto Llera, Sarah Meyer, Kaat Alaerts, Geert Verheyden, Stephan P. Swinnen, and Jesus M. Cortes. Multimodal lesion network mapping for prediction of sensorimotor behavior in stroke patients. OHBM 2022 – Organization for Human Brain Mapping [pdf] Introduction: Mapping the behavioral impact of brain lesions is of crucial importance for clinical practice. Regardless of the cause of the lesion, its size or the precise […]
Abstracts
Alberto Cabrera-Zubizarreta, Antonio Jimenez-Marin, Daniela Ramos-Usuga, Itziar Benito-Sanchez, Endika Martinez-Gutierrez, Victoria Boado, Fermin Labayen, Juan Carlos Arango-Lasprilla, and Jesus M. Cortes. Long-COVID: Aberrant connectivity of salience network in critically-ill patients. OHBM 2022 – Organization for Human Brain Mapping [pdf] Introduction: Long-COVID, a.k.a. post COVID syndrome, is a poorly defined systemic con-dition that encompasses fatigue, headaches and muscle aches, memory loss, sleep disorders, concentration problems and attention deficit, among other symptoms. […]
Endika Martínez Gutiérrez, Antonio Jiménez Marín, Sebastiano Stramaglia, and Jesus M. Cortes. Large scale brain organization of anti-correlated networks and their variations in the aging brain. OHBM 2022 – Organization for Human Brain Mapping [pdf] Introduction: Anatomically connected networks introduce statistical dependencies in the dynamics of the connected regions, inducing functional connectivity (FC). However, FC might also occur between regions with no direct anatomical connections, due to multiple effects such […]
Borja Camino-Pontes, Marilyn Gatica, Antonio Jimenez-Marin, Patricio Orio, Rodrigo Cofre, Jesus M Cortes. Modular structure of high-order interactions in the human brain. OHBM 2022 – Organization for Human Brain Mapping [pdf] Introduction: A network is highly modular when different communities of nodes have high intra-connectivity within them and low inter-connectivity between them. Different methods and strategies have been used to maximize modularity in brain networks, see for instance [1] and […]
Jesús M. Cortes, Borja Camino-Pontes, Antonio Jimenez-Marin, Iñaki Escudero, Beatriz Mateos, Alberto Cabrera-Zubizarreta, Miguel Ángel Muñoz, Sebastiano Stramaglia, Marta Subiran, Jorge Garcia-Condado, Paolo Bonifazi. Brain Hierarchical Atlas: Multi-Scale vs. Optimal Strategies in the Healthy and Pathological Brain. OHBM 2022 – Organization for Human Brain Mapping [pdf] Introduction: Elucidating the intricate relationship between brain structure and function is a classical –yet not fully understood– challenge for modern neuroscience. We developed the […]
Marilyn Gatica Briceño, Fernando E. Rosas, Pedro A.M. Mediano, Ibai Diez, Stephan P. Swinnen, Patricio Orio, Rodrigo Cofre, Jesus M. Cortes. HIGH-ORDER INTERACTIONS IN AGING EXPLAINED THROUGH CHANGES IN THE CONNECTOME IN A WHOLE-BRAIN MODEL. OHBM 2022 – Organization for Human Brain Mapping [pdf] Introduction: Previous studies of functional connectivity along the lifespan during resting state have shown that regions within the default mode network (DMN) become less functionally connected […]
Jesus M. Cortes, Paolo Bonifazi, Iñaki Escudero, Beatriz Mateos, Miguel Angel Muñoz, Sebastiano Stramaglia, Jesus M. Cortes, Borja Camino-Pontes, Antonio Jimenez-Marin, Javier Rasero, Asier Erramuzpe, Stephan Swinnen, Iñigo Gabilondo, Matthieu P. Boisgontier, Lisa Pauwels, Laiene Olabarrieta-Landa, Manuel Fernandez Martinez, Juan Carlos Arango Lasprilla, David Drijkoningen, Daniele Marinazzo, Jolien Gooijers, Ibai Diez. Brain Hierarchical Atlas: Multi-Scale versus Optimal Strategies in the Pathological Brain. OHBM 2019 – Organization for Human Brain Mapping […]
Borja Camino-Pontes, Ibai Diez, Antonio Jimenez-Marin, Javier Rasero, Asier Erramuzpe, Paolo Bonifazi, Sebastiano Stramaglia, Stephan Swinnen, Jesus M. Cortes. Interaction Information Along Lifespan Reveals a Redundant Role of the Default Mode Network. OHBM 2019 – Organization for Human Brain Mapping [pdf] Introduction: In this work recenty published (Camino-Pontes et al 2018), we show that the use of interaction information (II) can detect redundant or synergetic interactions in dynamical networks. De […]
Antonio Jimenez-Marin, Diego Rivera, Victoria Boado, Ibai Diez, Fermin Labayen, Irati Garrido, Daniela Ramos-Usuga, Javier Rasero, Alberto Cabrera-Zubizarreta, Iñigo Gabilondo, Sebastiano Stramaglia, Juan Carlos Arango Lasprilla, Jesus M. Cortes. Resting State Analysis in Multiorgan Failure Reveals Default Mode Network hyperconnectivity. OHBM 2019 – Organization for Human Brain Mapping [pdf] Introduction: Multiorgan Failure (MF) is a life-threating and potentially reversible condition that can affect patients admitted to Intensive Care Units (ICUs). […]
Paolo Bonifazi, Asier Erramuzpe, Ibai Diez, Iñigo Gabilondo, Matthieu P. Boisgontier, Lisa Pauwels, Sebastiano Stramaglia, Stephan Swinnen, Borja Camino-Pontes, Antonio Jimenez-Marin, Jesus M. Cortes. Structure-function multi-scale connectomics is an accurate predictor of brain aging. OHBM 2019 – Organization for Human Brain Mapping [pdf] Introduction: Aging is a dynamical process that encompasses a systemic time-dependent decline on multiple scales from biological to psychological and social levels. Interestingly, individuals with the same […]
Sebastaino Stramaglia, Javier Rasero, Jesus M. Cortes, Daniele Marinazzo, Ibai Diez. Connectome sorting by Consensus Clustering increases separability in group neuroimaging studies. OHBM 2019 – Organization for Human Brain Mapping [pdf] Introduction: A fundamental challenge in preprocessing pipelines for neuroimaging datasets is to increase the signal-to-noise ratio for subsequent analyses. This can be achieved for example by getting more compact groups before performing any statistical comparison. In this regard, the […]
Javier Rasero, Hannelore Aerts, Marlis Ontivero Ortega, Jesus M. Cortes, Sebastiano Stramaglia, Daniele Marinazzo. Functional Network prediction from region connectivity profiles and application to brain tumor data. OHBM 2019 – Organization for Human Brain Mapping [pdf] Introduction: Intrinsic Connectivity Networks (ICNs), patterns of correlated activity emerging from “resting- state” BOLD time series, are increasingly being associated with cognitive, clinical, and behavioral aspects, and compared with the pattern of activity elicited […]
Ibai Diez, David Drijkoningen, Sebastiano Stramaglia, Paolo Bonifazi, Daniele Marinazzo, Stephan P. Swinnen*, Jesus M. Cortes* (* Equal last-author contribution). Prefrontal brain connectivity re-organization after traumatic axonal injury. 22nd Annual Meeting of the Organization for Human Brain Mapping, OHBM 2016 [pdf] Background. Traumatic axonal injury damages brain structural connectivity which is later compensated by a re-organization in structural-functional circuits in a form which remains inadequately characterized. Methods. We enrolled N=14 […]
I Diez, P Bonifazi, I Escudero, B Mateos, MA Munoz, S Stramaglia, and JM Cortes. The Brain Hierarchical Atlas. 22nd Annual Meeting of the Organization for Human Brain Mapping , OHBM 2016 [pdf] Background. Most used brain atlases are purely anatomical or structural [1-4], and others are purely functional, like the well-known Brodmann atlas based on lesion studies or data-driven methods [5-6]. Although obtaining suitable brain partitions (or atlases) has […]
D. Marinazzo, M. Pellicoro, G. Wu, L. Angelini, J.M. Cortes and S. Stramaglia. Information transfer of an Ising model on a brain network. Computational NeuroScience (CNS) 2013 Meeting. BMC Neuroscience 2013, 14(Suppl 1):P376 We consider an anatomical connectivity matrix (66 nodes), obtained via diffusion spectrum imaging (DSI) and white matter tractography [1], describing the brain at a coarse scale, and implement on it an Ising model with Glauber dynamics, estimating […]
A Erramuzpe, GJ Ortega, J Pastor, RG de Sola, D Marinazzo, S Stramaglia and JM Cortes. Redundancy and synergetic circuits in inter-ictal activity of human temporal lobe epilepsy. Society for Neuroscience Annual Meeting 2014. The use of information theory in neuroscience have allowed to evaluate the interaction between groups of correlated variables, revealing their functional role and underlying circuits capable of processing information (Borst and Theunissen, 1999, Nat Neurosci; Panzeri […]
A Erramuzpe, JM Encinas, A Sierra, M Maletic-Savatic, AL Brewster, AE Anderson, S Stramaglia and JM M Cortes. Variations in whole-brain functional connectivity across seizure chronification in a mouse model of mesial temporal lobe epilepsy. Society for Neuroscience Annual Meeting 2014. How does the brain become epileptic? Although this is a major question for modern Neurology, we do not have yet a proper answer. Despite of intense research in the […]
I. Ortega-Martinez, J. Gardeazabal, A. Erramuzpe, R. Fernandez-Suarez, E. Alonso-Tejerina, G. Perez-Yarza, J.M. Cortes, I.M. de la Fuente, A. Asumendi and M.D. Boyano. Serum Proteomics in Melanoma Biomarker Discovery. 13th Annual World Congress of the Human Proteome Organization 2014. Introduction and objectives Patients with early-stage melanoma and no lymph node involvement have a high likelihood of cure after complete excision of the tumor by surgery. However, there is no effective […]
J.M. Cortes, J. Goñi, M.A. Muñoz and D.R. Chialvo. Generic dynamics at criticality links brain structure to function. Frontiers in Neuroinformatics, 2013 [pdf] The relation, influence, and constraints between structure and function of the human brain is not yet well understood, even for the widely studied resting state. In the last decade, different topological descriptors, and dynamical models such as neural mass or more complicated coupling models have shown how […]
V. Maki-Marttunen, J.M. Cortes, M. Villareal and D.R. Chialvo. Disruption of transfer entropy and inter-hemispheric brain functional connectivity in patients with disorder of consciousness. Computational NeuroScience (CNS) 2013 Meeting. BMC Neuroscience 2013, 14(Suppl 1):P83 [pdf] CNS 2013 Best Student Poster Award Winner. Recent studies suggest that the functional organization of brain networks is altered in patients with severe disorders of consciousness (DOC), including coma [1]. A better characterization of these […]
J.M. Cortes, D. Marinazzo, P. Series, M.W. Oram, T.J. Sejnowski and M.C.W. van Rossum. Neural adaptation reduces energy cost while preserving coding accuracy. Society for Neuroscience Annual Meeting 2010 Neurons in the primary visual cortex initially respond vigorously when a preferred stimulus is presented, but typically adapt as stimulation continues. The functional consequences of adaptation are unclear. Typically a reduction of firing reduces single neuron accuracy, but it has been […]
J.M. Cortes, D. Marinazzo, P. Tudela and E. Madrid. Causal connectivity analysis of tracking faces in presence of repeated distractors during working memory tasks. Society for Neuroscience Annual Meeting 2009 Recognition of a specific visual target among equally familiar distracters requires neural mechanisms for tracking items in working memory. High Density EEG recordings were obtained from sixteen right-handed normal participants while they performed a visual working memory task in which […]
L. Mancera, R. Jimenez-Galan, J.M. Cortes. Visual Information Processing trough a simulated retina: Linear vs Bayesian reconstruction of natural movies. Society for Neuroscience Annual Meeting 2009 In vision neuroscience much of the knowledge about information processing comes from experiments in presence of highly reduced stimuli: orientated bars, drifting gratings or dots and sometimes combinations of them. Very often, the implicit linearity of the stimuli works quite well to explain linear […]
J.M. Cortes, D. Marinazzo, P. Series, M. Oram, T.J. Sejnowski and M.C.W. van Rossum. Heterogeneous adaptation effects on visual population coding efficiency. COSYNE 2008: 5th Computational and Systems Neuroscience Meeting The cellular and synaptic mechanisms underlying visual adaptation have extensively been debated during the last years (for reviews see Kohn 2007 and Schwartz 2007). However, the effect of neural adaptation on information coding is difficult to study experimentally as it […]
J.M. Cortes, T.J. Sejnowski and M.C.W. van Rossum. Reverse Engineering: Weight dynamics consistent with experimental weight distributions. Society for Neuroscience Annual Meeting 2007 The strengths of synaptic connections that are responsible for perception and memory change on time scales ranging from milliseconds to many days. A key question is how memories can be made stable over long periods of time despite the ongoing synaptic plasticity. The distribution of synaptic weights […]
D. Marinazzo, J.M. Cortes, M. Postlethwaite and M. Hennig. Synaptic depression and multi-scale phenomena. Society for Neuroscience Annual Meeting 2007 How short term plasticity (STP) affects synaptic transmission has been widely studied during the last decade (Zucker and Regehr, 2001). During repetitive stimulation, a postsynaptic response can be facilitated or depressed or shaped by a combination of both. These effects have been successfully explained by models focusing on two main […]
J.M.A.M. Kusters, A.P.R. Theuvenet, D.L. Ypey, W.P.M. van Meerwijk, J.M. Cortes and C.C.A.M. Gielen. Calcium Oscillations driving an excitable membrane: Hysteresis and Bi-stability. Biophysical Society: 51th Annual Meeting. Biophysical Journal 257A-257A Suppl. S, 2007 In normal rat kidney (NRK) fibroblasts the excitable membrane exhibits action potentials caused by an intracellular, IP3-mediated calcium oscillation (CaO). We modeled that process in detail and applied bifurcation analysis to investigate the dynamic behaviour of […]