Antonio Jimenez-Marin, Nele De Bruyn, Jolien Gooijers, Alberto Llera, Sarah Meyer, Kaat Alaerts, Geert Verheyden, Stephan P. Swinnen, and Jesus M. Cortes. Multimodal lesion network mapping for prediction of sensorimotor behavior in stroke patients. OHBM 2022 – Organization for Human Brain Mapping [pdf] Introduction: Mapping the behavioral impact of brain lesions is of crucial importance for clinical practice. Regardless of the cause of the lesion, its size or the precise […]
Alberto Cabrera-Zubizarreta, Antonio Jimenez-Marin, Daniela Ramos-Usuga, Itziar Benito-Sanchez, Endika Martinez-Gutierrez, Victoria Boado, Fermin Labayen, Juan Carlos Arango-Lasprilla, and Jesus M. Cortes. Long-COVID: Aberrant connectivity of salience network in critically-ill patients. OHBM 2022 – Organization for Human Brain Mapping [pdf] Introduction: Long-COVID, a.k.a. post COVID syndrome, is a poorly defined systemic con-dition that encompasses fatigue, headaches and muscle aches, memory loss, sleep disorders, concentration problems and attention deficit, among other symptoms. […]
Endika Martínez Gutiérrez, Antonio Jiménez Marín, Sebastiano Stramaglia, and Jesus M. Cortes. Large scale brain organization of anti-correlated networks and their variations in the aging brain. OHBM 2022 – Organization for Human Brain Mapping [pdf] Introduction: Anatomically connected networks introduce statistical dependencies in the dynamics of the connected regions, inducing functional connectivity (FC). However, FC might also occur between regions with no direct anatomical connections, due to multiple effects such […]
Borja Camino-Pontes, Marilyn Gatica, Antonio Jimenez-Marin, Patricio Orio, Rodrigo Cofre, Jesus M Cortes. Modular structure of high-order interactions in the human brain. OHBM 2022 – Organization for Human Brain Mapping [pdf] Introduction: A network is highly modular when different communities of nodes have high intra-connectivity within them and low inter-connectivity between them. Different methods and strategies have been used to maximize modularity in brain networks, see for instance [1] and […]
Jesús M. Cortes, Borja Camino-Pontes, Antonio Jimenez-Marin, Iñaki Escudero, Beatriz Mateos, Alberto Cabrera-Zubizarreta, Miguel Ángel Muñoz, Sebastiano Stramaglia, Marta Subiran, Jorge Garcia-Condado, Paolo Bonifazi. Brain Hierarchical Atlas: Multi-Scale vs. Optimal Strategies in the Healthy and Pathological Brain. OHBM 2022 – Organization for Human Brain Mapping [pdf] Introduction: Elucidating the intricate relationship between brain structure and function is a classical –yet not fully understood– challenge for modern neuroscience. We developed the […]
Marilyn Gatica Briceño, Fernando E. Rosas, Pedro A.M. Mediano, Ibai Diez, Stephan P. Swinnen, Patricio Orio, Rodrigo Cofre, Jesus M. Cortes. HIGH-ORDER INTERACTIONS IN AGING EXPLAINED THROUGH CHANGES IN THE CONNECTOME IN A WHOLE-BRAIN MODEL. OHBM 2022 – Organization for Human Brain Mapping [pdf] Introduction: Previous studies of functional connectivity along the lifespan during resting state have shown that regions within the default mode network (DMN) become less functionally connected […]
Ha sido un placer charlar con una profesional del periodismo y de la comunicación como es Estíbaliz Ruiz de Azua. Puedes escuchar la entrevista en este audio. El link a la entrevista lo puedes encontrar aquí
Maider Nuñez-Ibero, Borja Camino-Pontes, Ibai Diez, Asier Erramuzpe, Endika Martinez-Gutierrez, Sebastiano Stramaglia, Javier O. Alvarez-Cienfuegos, and Jesus M. Cortes. A Controlled Thermoalgesic Stimulation Device for Exploring Novel Pain Perception Biomarkers. IEEE JOURNAL OF BIOMEDICAL AND HEALTH INFORMATICS 25: 2948-2957, 2021. biorxiv: [pdf] article: [pdf] Abstract Objective: To develop a new device for identifying physiological markers of pain perception by reading the brain’s electrical activity and hemodynamic interactions while applying thermoalgesic […]
2021, Que es la conectividad cerebral y como utilizarla en Investigacion clinica. Programa especial del 50 aniversario de la Universidad del Norte. Psicologia de la Salud: desafios contemporaneos y nuevas perspectivas. Univesidad del Norte, Barranquilla, Colombia
2021, Redes del cerebro, edad del conectoma, y como utilizarla para el estudio de patologias. Universidad del Valparaiso, Chile
Antonio Jimenez-Marin, Ibai Diez, Maria C. Caballero, Isidro Ferrer, Garazi Labayru, Pol Andres-Benito, Andone Sistiaga, Jorge Sepulcre, Adolfo Lopez de Munain, and Jesus M. Cortes. Transcriptional signatures of synaptic vesicle genes define myotonic dystrophy type I neurodegeneration. Neuropathology and Applied Neurobiology . In press, 2021. biorxiv: [pdf] article: [pdf] Abstract Aim: To delineate the neurogenetic profiles of brain degeneration patterns in myotonic dystrophy type I (DM1). Methods: In two cohorts […]
Changchun He, Heng Chen, Xiaonan Guo, Ruishi Wang, Lingyin Kong, Xinyue Huang, Huafu Chen, Jinming Xiao, Xiaolong Shan, Rui Feng, Xujun Duan. Individual-based morphological brain network organization and its association with autistic symptoms in young children with autism spectrum disorder. Human Brain Mapping. In press, 2021 [pdf] Abstract Individual-based morphological brain networks built from T1-weighted magnetic resonance imaging (MRI) reflect synchronous maturation intensities between anatomical regions at the individual level. […]
Leire Torices, Javier de las Heras, Juan Carlos Arango-Lasprilla, Jesús M. Cortes, Caroline E. Nunes-Xavier , Rafael Pulido. MMADHC premature termination codons in the pathogenesis of cobalamin D disorder: Potential of translational readthrough reconstitution. Molecular Genetics and Metabolism Reports. In press, 2021 [pdf] Abstract Mutations in the MMADHC gene cause cobalamin D disorder (cblD), an autosomal recessive inborn disease with defects in intracellular cobalamin (cbl, vitamin B12) metabolism. CblD patients […]
Sandra Luna, Leire Torices, Janire Mingo, Laura Amo, Isabel Rodríguez‐Escudero, Pablo Ruiz‐Ibarlucea, Asier Erramuzpe, Jesús M. Cortés, María I. Tejada, María Molina, Caroline E. Nunes‐Xavier, José I. López, Víctor J. Cid, and Rafael Pulido. A global analysis of the reconstitution of PTEN function by translational readthrough of PTEN pathogenic premature termination codons. Human Mutation. In press, 2021 [pdf] Abstract The PTEN tumor suppressor gene is mutated with high incidence in […]
Marilyn Gatica, Rodrigo Cofré, Pedro A.M. Mediano, Fernando E. Rosas, Patricio Orio, Ibai Diez, Stephan P. Swinnen, and Jesus M. Cortes. High-order interdependencies in the aging brain. Brain connectivity . In press, 2021. biorxiv: [pdf] article: [pdf] Abstract Background: Brain interdependencies can be studied from either a structural/anatomical perspective (“structural connectivity”-SC) or by considering statistical interdependencies (“functional connectivity”-FC). Interestingly, while SC is by definition pairwise (white-matter fibers project from one […]
JJ Torres, MA Muñoz, Jesus M Cortes, J Mejias. Special Issue on Emergent Effects in Stochastic Neural Networks with Application to Learning and Information Processing. Neurocomputing . In press, 2021. [pdf] Abstract This special issue includes a series of 12 articles, which represent a selection of extended contributions presented at the 15th Granada Seminar on Computational and Statistical Physics held in Granada from September 17 to 20, 2019, and organized […]
A Safari, P Moretti, I Diez, JM Cortes, MA Muñoz. Persistence of hierarchical network organization and emergent topologies in models of functional connectivity. Neurocomputing . In press, 2021. arxiv: [pdf] article: [pdf] Abstract Functional networks provide a topological description of activity patterns in the brain, as they stem from the propagation of neural activity on the anatomical or structural network of synaptic connections. This last is well known to be […]
I Fernandez-Iriondo, A Jimenez-Marin, I Diez, P Bonifazi, SP Swinnen, MA Munoz, JM Cortes. Low variability of dynamical functional connectivity in cerebellar networks. Neurocomputing . In press, 2021 biorxiv: [pdf] article: [pdf] Abstract Brain networks can be defined and explored using different types of connectivity. Here, we studied P=48 healthy participants with neuroimaging state-of-the-art techniques and analyzed the relationship between the actual structural connectivity (SC) networks (between 2514 regions of […]
Ane Murueta‐Goyena, Rocío Del Pino, Marta Galdós, Begoña Arana, Marian Acera, Mar Carmona‐Abellán, Tamara Fernández‐Valle, Beatriz Tijero, Olaia Lucas‐Jiménez, Natalia Ojeda, Naroa Ibarretxe‐Bilbao, Javier Peña, Jesus Cortes, Unai Ayala, Maitane Barrenechea, Juan Carlos Gómez‐Esteban, and Iñigo Gabilondo. Retinal Thickness Predicts the Risk of Cognitive Decline in Parkinson Disease. Annals of neurology 89: 165-176, 2021 [pdf] Abstract Objective: This study was undertaken to analyze longitudinal changes of retinal thickness and their […]
Garazi Labayru, Antonio Jimenez-Marin, Esther Fernandez, Jorge Villanua, Miren Zulaica, Jesus M. Cortes, Ibai Diıez, Jorge Sepulcre, Adolfo Lopez de Munain, Andone Sistiaga. Neurodegeneration trajectory in pediatric and adult/lateDM1: A follow-up MRI study across a decade. Annals of Clinical and Translational Neurology 7:1802-1815, 2020 [pdf] Abstract Objective: To characterize the progression of brain structural abnormalities in adults with pediatric and adult/late onset DM1, as well as to examine the potential […]
2020, Avances en conectividad de cerebral en enfermedades neurodegenerativas y en daño cerebral adquirido. XLVII SEMANA MÉDICA-NEUROLÓGICA. 28-30 sept, Bilbao, Spain
Informativo ITEMAS habla de nuestro proyecto financiado por primera vez a una institución española por la iniciativa Brain. This project, headed by Prof. Hasan in Achucarro, and where also participates Prof. Ramos in CIC-Biomagune and muyself, aims to achieve whole-brain imaging at cellular resolution You can watch the video at (in Spanish).
Javier De Las Heras, Ibai Diez, Antonio Jimenez-Marin, Alberto Cabrera, Daniela Ramos-Usuga, Marta Venecia Diaz-Fernandez, Leire Torices,Caroline E. Nunes-Xavier, Rafael Pulido, Juan Carlos Arango-Lasprilla, and Jesus M. Cortes. Brain Circuit Alterations and Cognitive Disability in Late-Onset Cobalamin D Disorder. J Clinical Medicine 9: 990, 2020 [pdf] Abstract Neuroimaging studies describing brain circuits’ alterations in cobalamin (vitamin B12)-deficient patients are limited and have not been carried out in patients with inborn […]
Changchun He, Huafu Chen, Lucina Q Uddin, Asier Erramuzpe, Paolo Bonifazi, Xiaonan Guo, Jinming Xiao, Heng Chen, Xinyue Huang, Lei Li, Wei Sheng, Wei Liao, Jesus M Cortes, and Xujun Duan. Structure-Function Connectomics Reveals Aberrant Developmental Trajectory Occurring at Preadolescence in the Autistic Brain. Cerebral Cortex 30: 5028–5037, 2020 [pdf] Abstract Accumulating neuroimaging evidence shows that age estimation obtained from brain connectomics reflects the level of brain maturation along with […]
Arrate Sevilla , Celia Morales, Pilar A. Ezkurra, Javier Rasero, Verónica Velasco, Goikoane Cancho-Galan, na Sánchez-Diez, armele Mujika, Cristina Penas, Isabel Smith, Aintzane Asumendi, Jesús M. Cortés, Maria Dolores Boyano, and Santos Alonso. BRAF V600E mutational load as a prognosis biomarker in malignant melanoma. Plos One 15:e0230136, 2020 [pdf] Abtstract Analyzing the mutational load of driver mutations in melanoma could provide valuable information regarding its progression. We aimed at analyzing […]
Yossi Mosbacher, Farad Khoyratee, Miri Goldin, Sivan Kanner, Yenehaetra Malakai, Moises Silva, Filippo Grassia, Yoav Ben Simon, Jesus Cortes, Ari Barzilai, Timothée Levi, and Paolo Bonifazi. Toward neuroprosthetic real-time communication from in silico to biological neuronal network via patterned optogenetic stimulation. Scientific Reports 10: 7512, 2020 [pdf] Abstract Restoration of the communication between brain circuitry is a crucial step in the recovery of brain damage induced by traumatic injuries or […]
Filippo Mancuso, Sergio Lage, Javier Rasero, José Luis Díaz‐Ramón, Aintzane Apraiz, Gorka Pérez‐Yarza, Pilar Ariadna Ezkurra, Cristina Penas, Ana Sánchez‐Diez, María Dolores García‐Vazquez, Jesús Gardeazabal, Rosa Izu, Karmele Mujika, Jesús Cortés, Aintzane Asumendi, and María Dolores Boyano. Serum markers improve current prediction of metastasis development in early‐stage melanoma patients: a machine learning‐based study. Molecular Oncology 14:1705-1718, 2020 [pdf] Abstract Metastasis development represents an important threat for melanoma patients, even when […]
Headed by Prof. Mazahir Hasan in the Achucarro Center for Neuroscience, and together with Prof. Pedro Ramos in CIC-Biomagune, we were the first team in Spain funded by the prestigious NIH-funded Brain Initiative. We aim to develop full-brain imaging genetic-technology at the cellular resolution. You can find more information at: https://www.ikerbasque.net/en/news/novel-genetic-technology-functional-mapping-entire-brain and in Spanish at: https://cadenaser.com/emisora/2020/05/28/radio_bilbao/1590659425_641261.html
Antonio Jimenez-Marin, Diego Rivera, Victoria Boado, Ibai Diez, Fermin Labayen, Irati Garrido, Daniela Ramos-Usuga, Itziar Benito-Sanchez, Javier Rasero, Alberto Cabrera Zubizarreta, Inigo Gabilondo, Sebastiano Stramaglia, Juan Carlos Arango-Lasprilla, Jesus M. Cortes. Brain Connectivity And Cognitive Functioning In Individuals Six Months After Multiorgan Failure Neuroimage: Clinical 25: 102137, 2020 [pdf] Abstract Multiorgan failure (MOF) is a life-threating condition that affects two or more systems of organs not involved in the disorder […]
Caroline E. Nunes-Xavier, Olaia Aurtenetxe, Laura Zaldumbide, Ricardo López-Almaraz, Asier Erramuzpe, Jesús M. Cortés, José I. López and Rafael Pulido. Protein tyrosine phosphatase PTPN1 modulates cell growth and associates with poor outcome in human neuroblastoma Diagnostic Pathology 14:134, 2019 [pdf] Abstract Background: Protein tyrosine phosphatases (PTPs) regulate neuronal differentiation and survival, but their expression patterns and functions in human neuroblastoma (NB) are scarcely known. Here, we have investigated the function […]