Marilyn Gatica, Fernando E. Rosas, Pedro A. M. Mediano, Ibai Diez, Stephan P. Swinnen, Patricio Orio, Rodrigo Cofre, Jesus M. Cortes. High-order functional redundancy in ageing explained via alterations in the connectome in a whole-brain model. PLoS Comput Biol 18(9): e1010431. [pdf] The human brain generates a rich repertoire of spatio-temporal activity patterns, which support a wide variety of motor and cognitive functions. These patterns of activity change with age […]
2022, Multiscale structure-function brain networks in health and disease. Complex networks: from socio-economic systems to biology and the brain. July 10-16, Lipari, Italy
Martin Iniguez, Antonio Jimenez-Marin, Asier Erramuzpe, Marian Acera, Beatriz Tijero, Ane Murueta-Goyena, Rocio Del Pino, Tamara Fernandez, Mar Carmona‑Abellan, Alberto Cabrera-Zubizarreta, Juan Carlos Gómez‑Esteban, Jesus M. Cortes and Inigo Gabilondo. Heart-brain synchronization breakdown in Parkinson’s disease. npj Parkinson’s Disease (2022) 64 [pdf] Heart rate variability (HRV) abnormalities are potential early biomarkers in Parkinson’s disease (PD) but their relationship with central autonomic network (CAN) activity is not fully understood. We analyzed […]
We have had a fantastic time together at OHBM Glasgow 2022 We presented 6 different posters on : Multimodal lesion network mapping [pdf] Long-covid functional connectivity study [pdf] Multiscale multimodal brain hierarchical atlas [pdf] Anticorrelated resting state networks of the human brain [pdf] Modular structure of high order interactions [pdf] Whole-brain modeling of aging and high-order interactions [pdf] We also have wonderful time enjoying Scotland and doing networking, see this […]
El Dr. Gabilondo habla en la cadena SER sobre nuestros últimos hallazgos de desincronización corazón-cerebro en la enfermedad del Parkinson Puedes escuchar el audio aquí
2022, Generación de mapas de desconexión cerebral para predecir comportamiento sensorimotor en pacientes con lesiones cerebrosvasculares. 36º Congreso Nacional Sociedad Española de Radiología Médica (SERAM). May 25-28, 2022. Malaga, Spain
2022, Disconectomica cerebral y sintomatología. Jornadas científicas y de reconocimiento a la investigación – Premios BioQ 2022. May 24-26, 2022. Barakaldo, Spain
Izaro Fernandez-Iriondo, Basilio Sierra, Jose Maria Martmez-Otzeta, Antonio Jimenez-Marin, Paolo Bonifazi, Yosu Yurramendi, and Jesus M. Cortes. Multiscale network regression for associations between brain connectivity and cognitive and behavioural indices. 2021 6th International Conference on Computational Intelligence and Applications (ICCIA). article: [pdf] Abstract The study of the relationship between brain connectivity and cognitive abilities is of great importance for a better understanding of the human mind. We propose to tackle […]
Izaro Fernandez-Iriondo, Antonio Jimenez-Marín, Basilio Sierra, Naiara Aginako, Paolo Bonifazi, and Jesus M. Cortes. Brain mapping of behavioral domains using multi-scale networks and canonical correlation analysis. Front. Neurosci. 2022. article: [pdf] Abstract Simultaneous mapping of multiple behavioral domains into brain networks remains a major challenge. Here, we shed some light on this problem by employing a combination of machine learning, structural and functional brain networks at different spatial resolutions (also […]
Rocío Del Pino, Marian Acera, Ane Murueta-Goyena, Olaia Lucas-Jimenez, Natalia Ojeda, Naroa Ibarretxe-Bilbao, Javier Pena, Paula Reyero, Jesus M Cortes, Beatriz Tijero, Marta Galdos, Juan Carlos Gomez-Esteban, Inigo Gabilondo. Visual dysfunction is associated with cognitive impairment in Parkinson’s disease. Parkinsonism and Related Disorders 92: 22–25, 2021. article: [pdf] Abstract Introduction: Visual dysfunction and cognitive impairment are common in Parkinson’s disease (PD) but the precise contribution of lower-level visual impairment to […]
Garazi Labayru, Borja Camino, Antonio Jimenez‑Marin, JoanaGarmendia , JorgeVillanua , Miren Zulaica, Jesus M. Cortes, Adolfo López de Munain & Andone Sistiaga. Scientific Reports 12:3988, 2022 article: [pdf] Abstract Myotonic Dystrophy Type 1 (DM1) is a multisystemic disease that afects gray and white matter (WM) tissues. WM changes in DM1 include increased hyperintensities and altered tract integrity distributed in a widespread manner. However, the precise temporal and spatial progression of […]
2022, Potpourri of practical cases using machine learning in biomedical research. AI4MED Talk Series. Artificial Inteligence (AI): a friend not an enemy to clinicians. Colegio de Medicos de Bizkaia, Bilbao, Spain
Ha sido un placer charlar con unos profesionales del periodismo y de la comunicación como son Juan Ramón Lucas y Alberto Aparicio. Puedes escuchar la entrevista en este audio. El link a la entrevista lo puedes encontrar aquí.
Antonio Jimenez-Marin, Nele De Bruyn, Jolien Gooijers, Alberto Llera, Sarah Meyer, Kaat Alaerts, Geert Verheyden, Stephan P. Swinnen, and Jesus M. Cortes. Multimodal lesion network mapping for prediction of sensorimotor behavior in stroke patients. OHBM 2022 – Organization for Human Brain Mapping [pdf] Introduction: Mapping the behavioral impact of brain lesions is of crucial importance for clinical practice. Regardless of the cause of the lesion, its size or the precise […]
Alberto Cabrera-Zubizarreta, Antonio Jimenez-Marin, Daniela Ramos-Usuga, Itziar Benito-Sanchez, Endika Martinez-Gutierrez, Victoria Boado, Fermin Labayen, Juan Carlos Arango-Lasprilla, and Jesus M. Cortes. Long-COVID: Aberrant connectivity of salience network in critically-ill patients. OHBM 2022 – Organization for Human Brain Mapping [pdf] Introduction: Long-COVID, a.k.a. post COVID syndrome, is a poorly defined systemic con-dition that encompasses fatigue, headaches and muscle aches, memory loss, sleep disorders, concentration problems and attention deficit, among other symptoms. […]
Endika Martínez Gutiérrez, Antonio Jiménez Marín, Sebastiano Stramaglia, and Jesus M. Cortes. Large scale brain organization of anti-correlated networks and their variations in the aging brain. OHBM 2022 – Organization for Human Brain Mapping [pdf] Introduction: Anatomically connected networks introduce statistical dependencies in the dynamics of the connected regions, inducing functional connectivity (FC). However, FC might also occur between regions with no direct anatomical connections, due to multiple effects such […]
Borja Camino-Pontes, Marilyn Gatica, Antonio Jimenez-Marin, Patricio Orio, Rodrigo Cofre, Jesus M Cortes. Modular structure of high-order interactions in the human brain. OHBM 2022 – Organization for Human Brain Mapping [pdf] Introduction: A network is highly modular when different communities of nodes have high intra-connectivity within them and low inter-connectivity between them. Different methods and strategies have been used to maximize modularity in brain networks, see for instance [1] and […]
Jesús M. Cortes, Borja Camino-Pontes, Antonio Jimenez-Marin, Iñaki Escudero, Beatriz Mateos, Alberto Cabrera-Zubizarreta, Miguel Ángel Muñoz, Sebastiano Stramaglia, Marta Subiran, Jorge Garcia-Condado, Paolo Bonifazi. Brain Hierarchical Atlas: Multi-Scale vs. Optimal Strategies in the Healthy and Pathological Brain. OHBM 2022 – Organization for Human Brain Mapping [pdf] Introduction: Elucidating the intricate relationship between brain structure and function is a classical –yet not fully understood– challenge for modern neuroscience. We developed the […]
Marilyn Gatica Briceño, Fernando E. Rosas, Pedro A.M. Mediano, Ibai Diez, Stephan P. Swinnen, Patricio Orio, Rodrigo Cofre, Jesus M. Cortes. HIGH-ORDER INTERACTIONS IN AGING EXPLAINED THROUGH CHANGES IN THE CONNECTOME IN A WHOLE-BRAIN MODEL. OHBM 2022 – Organization for Human Brain Mapping [pdf] Introduction: Previous studies of functional connectivity along the lifespan during resting state have shown that regions within the default mode network (DMN) become less functionally connected […]
Ha sido un placer charlar con una profesional del periodismo y de la comunicación como es Estíbaliz Ruiz de Azua. Puedes escuchar la entrevista en este audio. El link a la entrevista lo puedes encontrar aquí
Maider Nuñez-Ibero, Borja Camino-Pontes, Ibai Diez, Asier Erramuzpe, Endika Martinez-Gutierrez, Sebastiano Stramaglia, Javier O. Alvarez-Cienfuegos, and Jesus M. Cortes. A Controlled Thermoalgesic Stimulation Device for Exploring Novel Pain Perception Biomarkers. IEEE JOURNAL OF BIOMEDICAL AND HEALTH INFORMATICS 25: 2948-2957, 2021. biorxiv: [pdf] article: [pdf] Abstract Objective: To develop a new device for identifying physiological markers of pain perception by reading the brain’s electrical activity and hemodynamic interactions while applying thermoalgesic […]
2021, Que es la conectividad cerebral y como utilizarla en Investigacion clinica. Programa especial del 50 aniversario de la Universidad del Norte. Psicologia de la Salud: desafios contemporaneos y nuevas perspectivas. Univesidad del Norte, Barranquilla, Colombia
2021, Redes del cerebro, edad del conectoma, y como utilizarla para el estudio de patologias. Universidad del Valparaiso, Chile
Antonio Jimenez-Marin, Ibai Diez, Maria C. Caballero, Isidro Ferrer, Garazi Labayru, Pol Andres-Benito, Andone Sistiaga, Jorge Sepulcre, Adolfo Lopez de Munain, and Jesus M. Cortes. Transcriptional signatures of synaptic vesicle genes define myotonic dystrophy type I neurodegeneration. Neuropathology and Applied Neurobiology . In press, 2021. biorxiv: [pdf] article: [pdf] Abstract Aim: To delineate the neurogenetic profiles of brain degeneration patterns in myotonic dystrophy type I (DM1). Methods: In two cohorts […]
Changchun He, Heng Chen, Xiaonan Guo, Ruishi Wang, Lingyin Kong, Xinyue Huang, Huafu Chen, Jinming Xiao, Xiaolong Shan, Rui Feng, Xujun Duan. Individual-based morphological brain network organization and its association with autistic symptoms in young children with autism spectrum disorder. Human Brain Mapping. In press, 2021 [pdf] Abstract Individual-based morphological brain networks built from T1-weighted magnetic resonance imaging (MRI) reflect synchronous maturation intensities between anatomical regions at the individual level. […]
Leire Torices, Javier de las Heras, Juan Carlos Arango-Lasprilla, Jesús M. Cortes, Caroline E. Nunes-Xavier , Rafael Pulido. MMADHC premature termination codons in the pathogenesis of cobalamin D disorder: Potential of translational readthrough reconstitution. Molecular Genetics and Metabolism Reports. In press, 2021 [pdf] Abstract Mutations in the MMADHC gene cause cobalamin D disorder (cblD), an autosomal recessive inborn disease with defects in intracellular cobalamin (cbl, vitamin B12) metabolism. CblD patients […]
Sandra Luna, Leire Torices, Janire Mingo, Laura Amo, Isabel Rodríguez‐Escudero, Pablo Ruiz‐Ibarlucea, Asier Erramuzpe, Jesús M. Cortés, María I. Tejada, María Molina, Caroline E. Nunes‐Xavier, José I. López, Víctor J. Cid, and Rafael Pulido. A global analysis of the reconstitution of PTEN function by translational readthrough of PTEN pathogenic premature termination codons. Human Mutation. In press, 2021 [pdf] Abstract The PTEN tumor suppressor gene is mutated with high incidence in […]
Marilyn Gatica, Rodrigo Cofré, Pedro A.M. Mediano, Fernando E. Rosas, Patricio Orio, Ibai Diez, Stephan P. Swinnen, and Jesus M. Cortes. High-order interdependencies in the aging brain. Brain connectivity . In press, 2021. biorxiv: [pdf] article: [pdf] Abstract Background: Brain interdependencies can be studied from either a structural/anatomical perspective (“structural connectivity”-SC) or by considering statistical interdependencies (“functional connectivity”-FC). Interestingly, while SC is by definition pairwise (white-matter fibers project from one […]
JJ Torres, MA Muñoz, Jesus M Cortes, J Mejias. Special Issue on Emergent Effects in Stochastic Neural Networks with Application to Learning and Information Processing. Neurocomputing . In press, 2021. [pdf] Abstract This special issue includes a series of 12 articles, which represent a selection of extended contributions presented at the 15th Granada Seminar on Computational and Statistical Physics held in Granada from September 17 to 20, 2019, and organized […]
A Safari, P Moretti, I Diez, JM Cortes, MA Muñoz. Persistence of hierarchical network organization and emergent topologies in models of functional connectivity. Neurocomputing . In press, 2021. arxiv: [pdf] article: [pdf] Abstract Functional networks provide a topological description of activity patterns in the brain, as they stem from the propagation of neural activity on the anatomical or structural network of synaptic connections. This last is well known to be […]