Sandra Luna, Leire Torices, Janire Mingo, Laura Amo, Isabel Rodríguez‐Escudero, Pablo Ruiz‐Ibarlucea, Asier Erramuzpe, Jesús M. Cortés, María I. Tejada, María Molina, Caroline E. Nunes‐Xavier, José I. López, Víctor J. Cid, and Rafael Pulido. A global analysis of the reconstitution of PTEN function by translational readthrough of PTEN pathogenic premature termination codons. Human Mutation. In press, 2021 [pdf] Abstract The PTEN tumor suppressor gene is mutated with high incidence in […]
Marilyn Gatica, Rodrigo Cofré, Pedro A.M. Mediano, Fernando E. Rosas, Patricio Orio, Ibai Diez, Stephan P. Swinnen, and Jesus M. Cortes. High-order interdependencies in the aging brain. Brain connectivity . In press, 2021. biorxiv: [pdf] article: [pdf] Abstract Background: Brain interdependencies can be studied from either a structural/anatomical perspective (“structural connectivity”-SC) or by considering statistical interdependencies (“functional connectivity”-FC). Interestingly, while SC is by definition pairwise (white-matter fibers project from one […]
JJ Torres, MA Muñoz, Jesus M Cortes, J Mejias. Special Issue on Emergent Effects in Stochastic Neural Networks with Application to Learning and Information Processing. Neurocomputing . In press, 2021. [pdf] Abstract This special issue includes a series of 12 articles, which represent a selection of extended contributions presented at the 15th Granada Seminar on Computational and Statistical Physics held in Granada from September 17 to 20, 2019, and organized […]
A Safari, P Moretti, I Diez, JM Cortes, MA Muñoz. Persistence of hierarchical network organization and emergent topologies in models of functional connectivity. Neurocomputing . In press, 2021. arxiv: [pdf] article: [pdf] Abstract Functional networks provide a topological description of activity patterns in the brain, as they stem from the propagation of neural activity on the anatomical or structural network of synaptic connections. This last is well known to be […]
I Fernandez-Iriondo, A Jimenez-Marin, I Diez, P Bonifazi, SP Swinnen, MA Munoz, JM Cortes. Low variability of dynamical functional connectivity in cerebellar networks. Neurocomputing . In press, 2021 biorxiv: [pdf] article: [pdf] Abstract Brain networks can be defined and explored using different types of connectivity. Here, we studied P=48 healthy participants with neuroimaging state-of-the-art techniques and analyzed the relationship between the actual structural connectivity (SC) networks (between 2514 regions of […]
Ane Murueta‐Goyena, Rocío Del Pino, Marta Galdós, Begoña Arana, Marian Acera, Mar Carmona‐Abellán, Tamara Fernández‐Valle, Beatriz Tijero, Olaia Lucas‐Jiménez, Natalia Ojeda, Naroa Ibarretxe‐Bilbao, Javier Peña, Jesus Cortes, Unai Ayala, Maitane Barrenechea, Juan Carlos Gómez‐Esteban, and Iñigo Gabilondo. Retinal Thickness Predicts the Risk of Cognitive Decline in Parkinson Disease. Annals of neurology 89: 165-176, 2021 [pdf] Abstract Objective: This study was undertaken to analyze longitudinal changes of retinal thickness and their […]
Garazi Labayru, Antonio Jimenez-Marin, Esther Fernandez, Jorge Villanua, Miren Zulaica, Jesus M. Cortes, Ibai Diıez, Jorge Sepulcre, Adolfo Lopez de Munain, Andone Sistiaga. Neurodegeneration trajectory in pediatric and adult/lateDM1: A follow-up MRI study across a decade. Annals of Clinical and Translational Neurology 7:1802-1815, 2020 [pdf] Abstract Objective: To characterize the progression of brain structural abnormalities in adults with pediatric and adult/late onset DM1, as well as to examine the potential […]
2020, Avances en conectividad de cerebral en enfermedades neurodegenerativas y en daño cerebral adquirido. XLVII SEMANA MÉDICA-NEUROLÓGICA. 28-30 sept, Bilbao, Spain
Informativo ITEMAS habla de nuestro proyecto financiado por primera vez a una institución española por la iniciativa Brain. This project, headed by Prof. Hasan in Achucarro, and where also participates Prof. Ramos in CIC-Biomagune and muyself, aims to achieve whole-brain imaging at cellular resolution You can watch the video at (in Spanish).
Javier De Las Heras, Ibai Diez, Antonio Jimenez-Marin, Alberto Cabrera, Daniela Ramos-Usuga, Marta Venecia Diaz-Fernandez, Leire Torices,Caroline E. Nunes-Xavier, Rafael Pulido, Juan Carlos Arango-Lasprilla, and Jesus M. Cortes. Brain Circuit Alterations and Cognitive Disability in Late-Onset Cobalamin D Disorder. J Clinical Medicine 9: 990, 2020 [pdf] Abstract Neuroimaging studies describing brain circuits’ alterations in cobalamin (vitamin B12)-deficient patients are limited and have not been carried out in patients with inborn […]
Changchun He, Huafu Chen, Lucina Q Uddin, Asier Erramuzpe, Paolo Bonifazi, Xiaonan Guo, Jinming Xiao, Heng Chen, Xinyue Huang, Lei Li, Wei Sheng, Wei Liao, Jesus M Cortes, and Xujun Duan. Structure-Function Connectomics Reveals Aberrant Developmental Trajectory Occurring at Preadolescence in the Autistic Brain. Cerebral Cortex 30: 5028–5037, 2020 [pdf] Abstract Accumulating neuroimaging evidence shows that age estimation obtained from brain connectomics reflects the level of brain maturation along with […]
Arrate Sevilla , Celia Morales, Pilar A. Ezkurra, Javier Rasero, Verónica Velasco, Goikoane Cancho-Galan, na Sánchez-Diez, armele Mujika, Cristina Penas, Isabel Smith, Aintzane Asumendi, Jesús M. Cortés, Maria Dolores Boyano, and Santos Alonso. BRAF V600E mutational load as a prognosis biomarker in malignant melanoma. Plos One 15:e0230136, 2020 [pdf] Abtstract Analyzing the mutational load of driver mutations in melanoma could provide valuable information regarding its progression. We aimed at analyzing […]
Yossi Mosbacher, Farad Khoyratee, Miri Goldin, Sivan Kanner, Yenehaetra Malakai, Moises Silva, Filippo Grassia, Yoav Ben Simon, Jesus Cortes, Ari Barzilai, Timothée Levi, and Paolo Bonifazi. Toward neuroprosthetic real-time communication from in silico to biological neuronal network via patterned optogenetic stimulation. Scientific Reports 10: 7512, 2020 [pdf] Abstract Restoration of the communication between brain circuitry is a crucial step in the recovery of brain damage induced by traumatic injuries or […]
Filippo Mancuso, Sergio Lage, Javier Rasero, José Luis Díaz‐Ramón, Aintzane Apraiz, Gorka Pérez‐Yarza, Pilar Ariadna Ezkurra, Cristina Penas, Ana Sánchez‐Diez, María Dolores García‐Vazquez, Jesús Gardeazabal, Rosa Izu, Karmele Mujika, Jesús Cortés, Aintzane Asumendi, and María Dolores Boyano. Serum markers improve current prediction of metastasis development in early‐stage melanoma patients: a machine learning‐based study. Molecular Oncology 14:1705-1718, 2020 [pdf] Abstract Metastasis development represents an important threat for melanoma patients, even when […]
Headed by Prof. Mazahir Hasan in the Achucarro Center for Neuroscience, and together with Prof. Pedro Ramos in CIC-Biomagune, we were the first team in Spain funded by the prestigious NIH-funded Brain Initiative. We aim to develop full-brain imaging genetic-technology at the cellular resolution. You can find more information at: https://www.ikerbasque.net/en/news/novel-genetic-technology-functional-mapping-entire-brain and in Spanish at: https://cadenaser.com/emisora/2020/05/28/radio_bilbao/1590659425_641261.html
Antonio Jimenez-Marin, Diego Rivera, Victoria Boado, Ibai Diez, Fermin Labayen, Irati Garrido, Daniela Ramos-Usuga, Itziar Benito-Sanchez, Javier Rasero, Alberto Cabrera Zubizarreta, Inigo Gabilondo, Sebastiano Stramaglia, Juan Carlos Arango-Lasprilla, Jesus M. Cortes. Brain Connectivity And Cognitive Functioning In Individuals Six Months After Multiorgan Failure Neuroimage: Clinical 25: 102137, 2020 [pdf] Abstract Multiorgan failure (MOF) is a life-threating condition that affects two or more systems of organs not involved in the disorder […]
Caroline E. Nunes-Xavier, Olaia Aurtenetxe, Laura Zaldumbide, Ricardo López-Almaraz, Asier Erramuzpe, Jesús M. Cortés, José I. López and Rafael Pulido. Protein tyrosine phosphatase PTPN1 modulates cell growth and associates with poor outcome in human neuroblastoma Diagnostic Pathology 14:134, 2019 [pdf] Abstract Background: Protein tyrosine phosphatases (PTPs) regulate neuronal differentiation and survival, but their expression patterns and functions in human neuroblastoma (NB) are scarcely known. Here, we have investigated the function […]
Ildefonso M. De la Fuente, Carlos Bringas, Iker Malaina, Benjamin Regner, Alberto Pérez-Samartín, María Dolores Boyano, María Fedetz, José I. López, Gorka Pérez-Yarza, Jesus M. Cortes and Terrence Sejnowski. The nucleus does not significantly affect the migratory trajectories of amoeba in two-dimensional environments Scientific Reports 9:16369, 2019 [pdf] Abstract For a wide range of cells, from bacteria to mammals, locomotion movements are a crucial systemic behavior for cellular life. Despite […]
Garazi Labayru, Ibai Diez, Jorge Sepulcre, Esther Fernández, Miren Zulaica, Jesús M. Cortés, Adolfo López de Munain, Andone Sistiaga. Regional brain atrophy in gray and white matter is associated with cognitiveimpairment in Myotonic Dystrophy type 1 Neuroimage: Clinical 24: 102078, 2019 [pdf] Abstract Background Myotonic Dystrophy type 1 (DM1) is a slowly progressive myopathy characterized by varying multisystemic involvement. Several cerebral features such as brain atrophy, ventricular enlargement, and white […]
Peter beim Graben, Antonio Jimenez-Marin, Ibai Diez, Jesus M. Cortes, Mathieu Desroches and Serafim Rodrigues. Metastable Resting State Brain Dynamics. Frontiers in Computational Neuroscience 13:62, 2019 [pdf] Abstract Metastability refers to the fact that the state of a dynamical system spends a large amount of time in a restricted region of its available phase space before a transition takes place, bringing the system into another state from where it might […]
Together with other NeuroLagun colleagues, we have organised the second session of a divulgation seminar composed by several short-talks about ageing. Four different talks, Most prevalent neurodegenerative diseases in ageing (Iñigo Gabilondo), Treatment and care in the Basque Country (Juan Carlos Gomez), Rehabilitation (Juan Carlos Arango), Attention to the caregiver (Laiene Olabarrieta) The seminar is Tuesday Nov 26th 2019, at 6.00pm in Astra-Gernika
Together with other NeuroLagun colleagues, we have organised the second session of a divulgation seminar composed by several short-talks about ageing. Four different talks, Most prevalent neurodegenerative diseases in ageing (Iñigo Gabilondo), Treatment and care in the Basque Country (Juan Carlos Gomez), Rehabilitation (Juan Carlos Arango), Attention to the caregiver (Laiene Olabarrieta) The seminar is Thursday Oct 17th 2019, at 6.00pm in Goñi Portal
2019, Brain networks as a predictor of aging along lifespan. 15th Granada Seminar on Stochastic and Collective Effects in Neural Systems: Biological aspects, Modeling, Dynamics, Networks, Function and Applications. September 17-20, 2019. Granada, Spain
2019, Taller de Neuroimagen y Daño Cerebral. Precongreso del III Congreso Iberoamericano de Neuropsicologia y II Congreso de la Sociedad Colombiana de Neuropsicologia: Avances en la Disciplina. Universidad Pontificia Universidad Javeriana de Cali. 12-14 Septiembre 2019. Cali, Colombia.
2019, Mapeo de sintomas a redes del cerebro en daño cerebral. III Congreso Iberoamericano de Neuropsicologia y II Congreso de la Sociedad Colombiana de Neuropsicologia: Avances en la Disciplina. Universidad Pontificia Universidad Javeriana de Cali. 12-14 Septiembre 2019. Cali, Colombia.
2019, Brain networks as a predictor of aging along lifespan. Summer School in Computational and Theoretical Models in Neuroscience. Venice, Italy. September 9-14, 2019
2019, Brain networks as a predictor of aging along lifespan. am4ndalille – Advanced methods for neuroimaging data analysis workshop. University of Lille, France. September 2-3, 2019
2019, Brain networks as a predictor of aging along lifespan. Beacon Precision Imaging. University of Nottingham, UK. June 29, 2019