2018, Brain networks as a predictor of aging along lifespan. Institute Carlos I for Theoretical and Computational Physics. Granada, Spain
Iñigo Gabilondo, Verónica Llorens, Trinidad Rodriguez, Manuel Fernández, Tomas Pérez Concha, Marian Acera, Beatriz Tijero, Ane Murueta-Goyena, Rocío del Pino, Jesús Cortés, Juan Carlos Gómez-Esteban. Myocardial MIBG scintigraphy in genetic Parkinson’s disease as a model for Lewy body disorders. European Journal of Nuclear Medicine and Molecular Imaging, 46:376-384, 2019 [pdf] Purpose. To identify myocardial sympathetic denervation patterns suggestive of Lewy body (LB) pathology in patients with genetic and idiopathic parkinsonisms […]
2018, Brain networks as a predictor of aging along lifespan. COSTNET18 conference. Warsaw, Poland. September 26-28, 2018
Borja Camino-Pontes, Ibai Diez, Antonio Jimenez-Marin, Javier Rasero, Asier Erramuzpe, Paolo Bonifazi, Sebastiano Stramaglia, Stephan Swinnen and Jesus M. Cortes. Interaction Information Along Lifespan of the Resting Brain Dynamics Reveals a Major Redundant Role of the Default Mode Network. Entropy 20: 742, 2018 [pdf] Abstract Interaction Information (II) generalizes the univariate Shannon entropy to triplets of variables, allowing the detection of redundant (R) or synergetic (S) interactions in dynamical networks. […]
Olaia Aurtenetxe, Laura Zaldumbide, Asier erramuzpe, Ricardo Lpez, Jos I Lopez, Jess M Cortes, Rafael Pulido* and Caroline E Nunes-Xavier*. (*Equal last-author contribution). DUSP5 expression associates with poor prognosis in human neuroblastoma. Experimental and Molecular Pathology, 105:272-278, 2018 [pdf] Abstract Regulation of growth and differentiation of neuroblastoma (NB) cells is the rational of some maintenance therapies for high-risk NB. MAP kinase phosphatases (MKPs) are potential physiologic regulators of neuronal differentiation […]
Desconexión y reconfiguración de redes del cerebro tras traumatismo craneoencefálico. 12° Congreso de Investigación de Neurociencias Aplicadas de la Universidad Nacional Autónoma de Honduras (UNAH).
Paolo Bonifazi, Asier Erramuzpe, Ibai Diez, Iñigo Gabilondo, Matthieu P. Boisgontier, Lisa Pauwels, Sebastiano Stramaglia, Stephan P. Swinnen and Jesus M. Cortes. Structure–function multi-scale connectomics reveals a major role of the fronto-striato-thalamic circuit in brain aging. Human Brain Mapping, 39: 4663–4677, 2018 [pdf] Abstract Physiological aging affects brain structure and function impacting morphology, connectivity, and performance. However, whether some brain connectivity metrics might reflect the age of an individual is […]
Together with other NeuroLagun colleagues, we have organised the first session of a divulgation seminar composed by several short-talks about ageing. Four different talks, Neurogenesis (Juan Manuel Encinas), Imaging (Jesus M Cortes), Cognition (Laiene Olabarrieta) and Physical Activity as protected therapy (Gontzal Grandes). The seminar is Thursday June 14 2018, at 7.00pm in Nestor Basterretxea Aretoa.
In only 5 years after lab creation, we have got the accreditation of Consolidated of Excellence, according to indications of the National Institute of Health. This has been possible to all wonderful and talented researchers who have worked in the Computational Neuroimaging Laboratory at Biocruces. We are the only group formed by quantitative scientists (physicists and engineers) who has got this prestigious recognition, normally given to Clinical groups.
On May 7th, 2018 Asier Erramuzpe defended his Thesis titled “Development of new methods for brain connectivity biomarkers in epilepsy and other pathological conditions”. He got ”Cum Laude por Unaminidad”. Zorionak!!
2018, Brain connectivity for quantification of emergence, dysfunction and reorganization of the pathological brain. Seminars organized by the Neurodegenerative Diseases Group at Biocruces. Barakaldo, Spain
2018, La neuroimagen computacional. Una recreación funcional de la neuroanatomia. Ciclo de conferencias FME 50 Urte. Leioa, Spain
In collaboration with Luca Gerardo – Giorda (BCAM, Bilbao) and Sebastiano Stramaglia (Univ of Bari), we are organizing the 2018 Quantitative Biomedicine Workshop. Further information (program and registration info) can be found at http://www.bcamath.org/en/workshops/qbio2018 The poster conference [pdf] The book of abstracts [pdf]
T. Lissek., et. al. , M.T. Hasan. Building Bridges through Science. Neuron 96:730-735, 2017 [pdf] Science is ideally suited to connect people from different cultures and thereby foster mutual understanding. To promote international life science collaboration, we have launched ‘‘The Science Bridge’’ initiative. Our current project focuses on partnership between Western and Middle Eastern neuroscience communities.
I am Ikerbasque Research Professor (hosted by the new created BioCruces) Further information: 1. Visit its website 2. Watch this introductory video 3. Read this dossier 4. Watch the video on the 2014 scientific output 5. Read the research strategy for the years 2018-2021 Annual Reports: 1. 2007-2011 scientific output 2. 2012 scientific output 3. 2013 scientific output 4. 2014 scientific output 5. 2015 scientific output 6. 2017 scientific output […]
2017, From multimodal images to connectivity of brain networks in both healthy and pathological conditions. COSTNET17 Conference. Mallorca, Spain
2017, Brain disconnectivity after traumatic brain injury. 3rd ANNUAL NEUROSCIENCE CONFERENCE. Aga Khan University. Karachi, Pakistan
A. Erramuzpe, JM Cortes and JI Lopez. Multisite tumor sampling enhances the detection of intratumor heterogeneity at all different temporal stages of tumor evolution. Virchows Arch 472:187-194, 2018 [pdf] Abstract Intratumor heterogeneity (ITH) is an inherent process of tumor development that has received much attention in previous years, as it has become a major obstacle for the success of targeted therapies. ITH is also temporally unpredictable across tumor evolution, which […]
Javier Rasero*, Carmen Alonso Montes*, Ibai Diez*, Laiene Olabarrieta-Landa, Lakhdar Remaki, Iñaki Escudero, Beatriz Mateos Goñi, Paolo Bonifazi, Manuel Fernandez Martinez, Juan Carlos Arango-Lasprilla, Sebastiano Stramaglia** and Jesus Cortes** (*Equal first-author contribution) (**Equal last-author contribution). Group-Level Progressive Alterations in Brain Connectivity Patterns Revealed by Diffusion-Tensor Brain Networks across Severity Stages in Alzheimer’s Disease. Frontiers in Aging Neuroscience 9:215, 2017 [pdf] Alzheimer’s disease (AD) is a chronically progressive neurodegenerative disease highly […]
J Rasero, M Pellicoro, L Angellini, JM Cortes, D Marinazzo, S Stramaglia. Consensus clustering approach to group brain connectivity matrices. Network Neuroscience 1: 242-253, 2017 [pdf] A novel approach rooted on the notion of consensus clustering, a strategy developed for community detection in complex networks, is proposed to cope with the heterogeneity that characterizes connectivity matrices in health and disease. The method can be summarized as follows: (i) define, for […]
JM Cortes, Giovanni de Petris, JI Lopez. Detection of intra-tumor heterogeneity in modern pathology: A multi-site tumor sampling (MSTS) perspective. Frontiers in Medicine 4:25 , 2017 [pdf] Current sampling protocols of neoplasms along the digestive tract and in the urinary bladder have to be updated, as they do not respond to the necessities of modern personalized medicine. We show here that an adapted version of multisite tumor sampling (MSTS) is […]
JM Kroos, I Marinelli, I Diez, JM Cortes, S Stramaglia, and L Gerardo-Giorda. Patient-specific computational modeling of Cortical Spreading Depression via Diffusion Tensor Imaging. International Journal for Numerical Methods in Biomedical Engineering, 2017 [pdf] Cortical spreading depression, a depolarization wave originating in the visual cortex and traveling towards the frontal lobe, is commonly accepted as a correlate of migraine visual aura. As of today, little is known about the mechanisms […]
2017. From multimodal images to connectivity of brain networks in both healthy and pathological conditions. Friedrich-Alexander-Universitt, Germany
2017. Evidence and future in neuroimaging and brain connectivitty in Sanfilippo Syndrome. Mead Johnson Bilbao, Spain
S. Stramaglia, M. Pellicoro, L. Angelini, E. Amico, H. Aerts, J.M. Cortes, S. Laureys, and D. Marinazzo. Ising Model with conserved magnetization on the Human Connectome: implications on the relation structure-function in wakefulness and anesthesia. Chaos 27: 047407, 2017 [pdf] Dynamical models implemented on the large scale architecture of the human brain may shed light on how function arises from the underlying structure.This is the case notably for simple abstract […]
Jose Ignacio Lopez and Jesus M Cortes. Multi-Site Tumor Sampling (MSTS): A new tumor selection method to enhance intratumor heterogeneity detection. Human Pathology 64:1-6, 2017 [pdf] Intratumor heterogeneity (ITH) is increasingly being recognized as a highly complex process with high clinical impact that deserves special attention from practicing pathologists. The goodness of the ITH detection depends on the correctness of the pathologist’s sampling. The goal of this review is twofold. […]
Ildefonso de la Fuente, Iker Malaina, Alberto Perez-Samartin, Maria D. Boyano, Gorka Perez- Yarza, Carlos Bringas, Alvaro Villarroel, Maria Fedetz, Jesus M Cortes and Luis Martinez. Dynamic properties of calcium-activated chloride currents in Xenopus laevis oocytes. Scientific Reports 7:41791, 2017 [pdf] Chloride is the most abundant permeable anion in the cell, and numerous studies in the last two decades highlight the great importance and broad physiological role of chloride currents […]