2018, La neuroimagen computacional. Una recreación funcional de la neuroanatomia. Ciclo de conferencias FME 50 Urte. Leioa, Spain
In collaboration with Luca Gerardo – Giorda (BCAM, Bilbao) and Sebastiano Stramaglia (Univ of Bari), we are organizing the 2018 Quantitative Biomedicine Workshop. Further information (program and registration info) can be found at http://www.bcamath.org/en/workshops/qbio2018 The poster conference [pdf] The book of abstracts [pdf]
T. Lissek., et. al. , M.T. Hasan. Building Bridges through Science. Neuron 96:730-735, 2017 [pdf] Science is ideally suited to connect people from different cultures and thereby foster mutual understanding. To promote international life science collaboration, we have launched ‘‘The Science Bridge’’ initiative. Our current project focuses on partnership between Western and Middle Eastern neuroscience communities.
I am Ikerbasque Research Professor (hosted by the new created BioCruces) Further information: 1. Visit its website 2. Watch this introductory video 3. Read this dossier 4. Watch the video on the 2014 scientific output 5. Read the research strategy for the years 2018-2021 Annual Reports: 1. 2007-2011 scientific output 2. 2012 scientific output 3. 2013 scientific output 4. 2014 scientific output 5. 2015 scientific output 6. 2017 scientific output […]
2017, From multimodal images to connectivity of brain networks in both healthy and pathological conditions. COSTNET17 Conference. Mallorca, Spain
2017, Brain disconnectivity after traumatic brain injury. 3rd ANNUAL NEUROSCIENCE CONFERENCE. Aga Khan University. Karachi, Pakistan
A. Erramuzpe, JM Cortes and JI Lopez. Multisite tumor sampling enhances the detection of intratumor heterogeneity at all different temporal stages of tumor evolution. Virchows Arch 472:187-194, 2018 [pdf] Abstract Intratumor heterogeneity (ITH) is an inherent process of tumor development that has received much attention in previous years, as it has become a major obstacle for the success of targeted therapies. ITH is also temporally unpredictable across tumor evolution, which […]
Javier Rasero*, Carmen Alonso Montes*, Ibai Diez*, Laiene Olabarrieta-Landa, Lakhdar Remaki, Iñaki Escudero, Beatriz Mateos Goñi, Paolo Bonifazi, Manuel Fernandez Martinez, Juan Carlos Arango-Lasprilla, Sebastiano Stramaglia** and Jesus Cortes** (*Equal first-author contribution) (**Equal last-author contribution). Group-Level Progressive Alterations in Brain Connectivity Patterns Revealed by Diffusion-Tensor Brain Networks across Severity Stages in Alzheimer’s Disease. Frontiers in Aging Neuroscience 9:215, 2017 [pdf] Alzheimer’s disease (AD) is a chronically progressive neurodegenerative disease highly […]
J Rasero, M Pellicoro, L Angellini, JM Cortes, D Marinazzo, S Stramaglia. Consensus clustering approach to group brain connectivity matrices. Network Neuroscience 1: 242-253, 2017 [pdf] A novel approach rooted on the notion of consensus clustering, a strategy developed for community detection in complex networks, is proposed to cope with the heterogeneity that characterizes connectivity matrices in health and disease. The method can be summarized as follows: (i) define, for […]
JM Cortes, Giovanni de Petris, JI Lopez. Detection of intra-tumor heterogeneity in modern pathology: A multi-site tumor sampling (MSTS) perspective. Frontiers in Medicine 4:25 , 2017 [pdf] Current sampling protocols of neoplasms along the digestive tract and in the urinary bladder have to be updated, as they do not respond to the necessities of modern personalized medicine. We show here that an adapted version of multisite tumor sampling (MSTS) is […]
JM Kroos, I Marinelli, I Diez, JM Cortes, S Stramaglia, and L Gerardo-Giorda. Patient-specific computational modeling of Cortical Spreading Depression via Diffusion Tensor Imaging. International Journal for Numerical Methods in Biomedical Engineering, 2017 [pdf] Cortical spreading depression, a depolarization wave originating in the visual cortex and traveling towards the frontal lobe, is commonly accepted as a correlate of migraine visual aura. As of today, little is known about the mechanisms […]
2017. From multimodal images to connectivity of brain networks in both healthy and pathological conditions. Friedrich-Alexander-Universitt, Germany
2017. Evidence and future in neuroimaging and brain connectivitty in Sanfilippo Syndrome. Mead Johnson Bilbao, Spain
S. Stramaglia, M. Pellicoro, L. Angelini, E. Amico, H. Aerts, J.M. Cortes, S. Laureys, and D. Marinazzo. Ising Model with conserved magnetization on the Human Connectome: implications on the relation structure-function in wakefulness and anesthesia. Chaos 27: 047407, 2017 [pdf] Dynamical models implemented on the large scale architecture of the human brain may shed light on how function arises from the underlying structure.This is the case notably for simple abstract […]
Jose Ignacio Lopez and Jesus M Cortes. Multi-Site Tumor Sampling (MSTS): A new tumor selection method to enhance intratumor heterogeneity detection. Human Pathology 64:1-6, 2017 [pdf] Intratumor heterogeneity (ITH) is increasingly being recognized as a highly complex process with high clinical impact that deserves special attention from practicing pathologists. The goodness of the ITH detection depends on the correctness of the pathologist’s sampling. The goal of this review is twofold. […]
Ildefonso de la Fuente, Iker Malaina, Alberto Perez-Samartin, Maria D. Boyano, Gorka Perez- Yarza, Carlos Bringas, Alvaro Villarroel, Maria Fedetz, Jesus M Cortes and Luis Martinez. Dynamic properties of calcium-activated chloride currents in Xenopus laevis oocytes. Scientific Reports 7:41791, 2017 [pdf] Chloride is the most abundant permeable anion in the cell, and numerous studies in the last two decades highlight the great importance and broad physiological role of chloride currents […]
Jose Ignacio Lopez, Asier Erramuzpe, Rosa Guarch, Jesus M Cortes, Roberto Llarena and Javier C Angulo. CD34 immunostaining enhances a distinct pattern of intratumor angiogenesis with prognostic implications in clear cell renal cell carcinoma. APMIS 125: 128-133, 2017 [pdf] Clear cell renal cell carcinoma is an aggressive neoplasm related to VHL gene inactivation. The molecular events derived from this initial alteration lead to a permanent intracellular pseudo-hypoxic status that stimulates […]
Being part of the Brainhack Global series, and organized by Asier Erramuzpe, we are local hosting the Brainhack- Global event in Bilbao, March 2-4, 2017 Further information at https://www.eventbrite.es/e/entradas-brainhack-bilbao-31508133676
In collaboration with Luca Gerardo – Giorda (BCAM, Bilbao) and Sebastiano Stramaglia (Univ of Bari), we are organizing the 2017 Quantitative Biomedicine Workshop. Further information (program and registration info) can be found at http://www.bcamath.org/en/workshops/qbio2017 The poster conference [pdf] The book of abstracts [pdf]
A privilege to work with such wonderful people, from left to right, Asier Erramuzpe, Paolo Bonifazi, Jesus Cortes, Beatriz Mateos, Ibai Diez, Iñaki Escudero and Javier Rasero.
2016, Brain connectivity methods in humans and their application to different pathologies. Andes University. Bogota, Colombia
2016, Connectivity and Disconnectivity after Traumatic Brain Injury. Invited talk. Sexto Congreso Internacional de Neuropsicologia Intrahospitalaria. Bogota, Colombia
2016, Brain connectivity methods in humans and their application to different pathologies. University of Antioquia. Medellin, Colombia
My collaboration with Dr. JI Lopez on a new method for tumor sampling called Multi-Site Tumor Sampling went to the so prestigious journal The Pathologist Here, you can download the pdf Here, you can visit the website
From the interaction between different people with common interests and ambitions, we have created and are participating in the neurokafe. More information at https://neurokafe.github.io/
Ibai Diez, David Drijkoningen, Sebastiano Stragmalia, Paolo Bonifazi, Daniele Marinazzo, Jolien Gooijers, Stephan P. Swinnen, Jesus M. Cortes. Enhanced pre-frontal functional-structural networks to support postural control deficits after traumatic brain injury in a pediatric population. Network Neuroscience 1: 116-142, 2017 [pdf] Preprint at [pdf] Traumatic brain injury (TBI) affects the structural connectivity, triggering the re-organization of structural-functional circuits in a manner that remains poorly understood. We focus here on brain […]
J Mingo, A Erramuzpe, S Luna, I Diez, JM Cortes and R Pulido. One-Tube-Only Standardized Site-Directed Mutagenesis: An Alternative Approach to Generate Amino Acid Substitution Collections. PLoS One 11: e0160972, 2016 [pdf] Site-directed mutagenesis (SDM) is a powerful tool to create defined collections of protein variants for experimental and clinical purposes, but effectiveness is compromised when a large number of mutations is required. We present here a one-tube-only standardized SDM […]