Yearly Archives: 2025

Francesca Santucci, Antonio Jimenez-Marin, Andrea Gabrielli, Paolo Bonifazi, Miguel Ibáñez-Berganza, Tommaso Gili, and Jesus M. Cortes.Partial correlation as a tool for mapping functional-structural correspondence in human brain connectivity. Network Neuroscience 2025. [pdf] Abstract: Brain structure-function coupling has been studied in health and disease by many different researchers in recent years. Most of the studies have estimated functional connectivity matrices as correlation coefficients between different brain areas, despite well-known disadvantages compared […]

Clara Inesta, Beatriz Bonete-Lopez, Javier Oltra-Cucarella, Borja Camino-Pontes, Jesus M. Cortes, Juan Carlos Arango-Lasprilla, Esther Sitges-Macia. Does engagement in cognitive activities contribute to the preservation of brain structure and connectivity in older adults?. Journal of the Neurological Sciences 477: 123658, 2025 [pdf] Abstract Aging is associated with changes in brain structure and connectivity and decrements in certain cognitive abilities. The benefits of active lifestyles in the aging brain and cognition […]

Geraldine Rodríguez-Nieto, Caroline Seer, Hamed Zivari Adab, Antonio Jiménez-Marín, Sima Chalavi, Amirhossein Rasooli, Jesus M. Cortes, Stefan Sunaert, Stephan P. Swinnen. Efficiency of Structural Brain Networks Mediates Age-Associated Differences in Executive Functioning in Older Adults. Frontiers in Aging Neuroscience, 2025. [pdf] Abstract Older age is associated with alterations in executive functioning (EF). Age-related alterations in the integrity of structural brain networks may contribute to EF decline, with potential consequences for […]

Changchun He, Jesus M. Cortes, Yi Ding, Xiaolong Shan, Maoyang Zou, Heng Chen, Huafu Chen, Xianmin Wang, Xujun Duan. Brain Imaging and Behavior, 2025. [pdf] Abstract Accumulating neuroimaging evidence suggests that abnormal functional and structural brain connectivity plays a cardinal role in the pathophysiology of autism spectrum disorder (ASD). Here, we constructed brain networks of functional, structural, and morphological connectivity using data from functional magnetic resonance imaging (fMRI), diffusion tensor […]

Marlis Ontivero-Ortega, Luca Faes, Jesus M. Cortes, Daniele Marinazzo, and Sebastiano Stramaglia. Assessing high-order effects in feature importance via predictability decomposition. Physical Review 111: L033301, 2025. [pdf] Abstract Building on recent advances in describing redundancy and synergy in multivariate interactions among random variables, we propose an approach to quantify cooperative effects in feature importance, a key technique in explainable artificial intelligence. Specifically, we introduce an adaptive version of the widely […]

Asier Erramuzpe, Ane Murueta-Goyena, Antonio Jimenez-Marin, Marian Acera, Sara Teijeira-Portas, Rocío Del Pino, Tamara Fernández-Valle, Ibai Diez, Unai Sainz-Lugarezaresti, Naroa Ibarretxe-Bilbao, Unai Ayala, Maitane Barrenechea, Alberto Cabrera-Zubizarreta, Jesús Cortés, Juan Carlos Gómez-Esteban, Iñigo Gabilondo. Amygdala Neurodegeneration: A Key Driver of VisualDysfunction in Parkinson’s Disease. Ann Clin Transl Neurol 12: 768-779, 2025. [pdf] Abstract Objective: Visual disability in Parkinson’s disease (PD) is not fully explained by retinal neurodegeneration. We aimed to […]

Jorge Garcia Condado, Iñigo Tellaetxe-Elorriaga, Jesus M. Cortes, and Asier Erramuzpe. AgeML: Age Modeling With Machine Learning. IEEE Journal of Biomedical and Health Informatics: 29, 3772-3781, 2025. [pdf] Abstract An approach to age modeling involves the supervised prediction of age using machine learning from subject features. The derived age metrics are used to study the relationship between healthy and pathological aging in multiple body systems, as well as the interactions […]

Joana Garmendia, Garazi Labayru, Antonio Jiménez-Marín, Jorge Villanúa, Jesús Cortés, Adolfo López de Munain and Andone Sistiaga. Hyperconnectivity in resting-state fMRI as a marker of disease severity in Myotonic Dystrophy Type 1. J Neuromuscul Dis 2025; 12: 90–101. [pdf] Abstract Introduction: Myotonic dystrophy type 1 (DM1) patients show both structural and functional brain alterations, including abnormal resting-state (RS) functional connectivity. Although some studies have investigated RS functional connectivity in DM1, […]