Jose I. Lopez, Rafael Pulido, Jesus M. Cortes , Javier C. Angulo, and Charles H. Lawrie. Potential impact of PD-L1 (SP-142) immunohistochemical heterogeneity in clear cell renal cell carcinoma immunotherapy. Pathol Res Pract 214:1110-1114, 2018 [pdf] Abstract Intratumor heterogeneity (ITH) detection remains a challenge in modern oncology because it can have a direct impact on the success of new therapies. Anti-PD-1/PD-L1 immunotherapy is an emerging treatment modality that is showing great promise for […]
Yearly Archives: 2018
Together with other NeuroLagun colleagues, we have organised the second session of a divulgation seminar composed by several short-talks about ageing. Four different talks, Most prevalent neurodegenerative diseases in ageing (Iñigo Gabilondo), Treatment and care in the Basque Country (Juan Carlos Gomez), Rehabilitation (Juan Carlos Arango), Attention to the caregiver (Laiene Olabarrieta) The seminar is Tuesday Dec 18 2018, at 7.00pm in Nestor Basterretxea Aretoa
2018, A brain hierarchical atlas to study the pathological brain. Andalusian Institute for Data Science and Computational Intelligence. Granada, Spain
Javier Rasero, Ibai Diez, Jesus M Cortes, Daniele Marinazzo and Sebastiano Stramaglia. Connectome sorting by Consensus Clustering increases separability in group neuroimaging studies. Network Neuroscience , 3: 325–343, 2018 [pdf] Abstract A fundamental challenge in preprocessing pipelines for neuroimaging datasets is to increase the signal-to-noise ratio for subsequent analyses. In the same line, we suggest here that the application of the consensus clustering approach to brain connectivity matrices can be […]
Javier Rasero, Hannelore Aerts, Marlis Ontivero Ortega, Jesus M. Cortes, Sebastiano Stramaglia , Daniele Marinazzo. Predicting functional networks from region connectivity profiles in task-based versus resting-state fMRI data PLoS One, 13: e0207385, 2018 [pdf] Abstract Intrinsic Connectivity Networks, patterns of correlated activity emerging from “resting-state” BOLD time series, are increasingly being associated with cognitive, clinical, and behavioral aspects, and compared with patterns of activity elicited by specific tasks. We study […]
2018, Brain networks as a predictor of aging along lifespan. Institute Carlos I for Theoretical and Computational Physics. Granada, Spain
Iñigo Gabilondo, Verónica Llorens, Trinidad Rodriguez, Manuel Fernández, Tomas Pérez Concha, Marian Acera, Beatriz Tijero, Ane Murueta-Goyena, Rocío del Pino, Jesús Cortés, Juan Carlos Gómez-Esteban. Myocardial MIBG scintigraphy in genetic Parkinson’s disease as a model for Lewy body disorders. European Journal of Nuclear Medicine and Molecular Imaging, 46:376-384, 2019 [pdf] Purpose. To identify myocardial sympathetic denervation patterns suggestive of Lewy body (LB) pathology in patients with genetic and idiopathic parkinsonisms […]
2018, Brain networks as a predictor of aging along lifespan. COSTNET18 conference. Warsaw, Poland. September 26-28, 2018
Borja Camino-Pontes, Ibai Diez, Antonio Jimenez-Marin, Javier Rasero, Asier Erramuzpe, Paolo Bonifazi, Sebastiano Stramaglia, Stephan Swinnen and Jesus M. Cortes. Interaction Information Along Lifespan of the Resting Brain Dynamics Reveals a Major Redundant Role of the Default Mode Network. Entropy 20: 742, 2018 [pdf] Abstract Interaction Information (II) generalizes the univariate Shannon entropy to triplets of variables, allowing the detection of redundant (R) or synergetic (S) interactions in dynamical networks. […]
Olaia Aurtenetxe, Laura Zaldumbide, Asier erramuzpe, Ricardo Lpez, Jos I Lopez, Jess M Cortes, Rafael Pulido* and Caroline E Nunes-Xavier*. (*Equal last-author contribution). DUSP5 expression associates with poor prognosis in human neuroblastoma. Experimental and Molecular Pathology, 105:272-278, 2018 [pdf] Abstract Regulation of growth and differentiation of neuroblastoma (NB) cells is the rational of some maintenance therapies for high-risk NB. MAP kinase phosphatases (MKPs) are potential physiologic regulators of neuronal differentiation […]
Desconexión y reconfiguración de redes del cerebro tras traumatismo craneoencefálico. 12° Congreso de Investigación de Neurociencias Aplicadas de la Universidad Nacional Autónoma de Honduras (UNAH).
Paolo Bonifazi, Asier Erramuzpe, Ibai Diez, Iñigo Gabilondo, Matthieu P. Boisgontier, Lisa Pauwels, Sebastiano Stramaglia, Stephan P. Swinnen and Jesus M. Cortes. Structure–function multi-scale connectomics reveals a major role of the fronto-striato-thalamic circuit in brain aging. Human Brain Mapping, 39: 4663–4677, 2018 [pdf] Abstract Physiological aging affects brain structure and function impacting morphology, connectivity, and performance. However, whether some brain connectivity metrics might reflect the age of an individual is […]
Together with other NeuroLagun colleagues, we have organised the first session of a divulgation seminar composed by several short-talks about ageing. Four different talks, Neurogenesis (Juan Manuel Encinas), Imaging (Jesus M Cortes), Cognition (Laiene Olabarrieta) and Physical Activity as protected therapy (Gontzal Grandes). The seminar is Thursday June 14 2018, at 7.00pm in Nestor Basterretxea Aretoa.
In only 5 years after lab creation, we have got the accreditation of Consolidated of Excellence, according to indications of the National Institute of Health. This has been possible to all wonderful and talented researchers who have worked in the Computational Neuroimaging Laboratory at Biocruces. We are the only group formed by quantitative scientists (physicists and engineers) who has got this prestigious recognition, normally given to Clinical groups.
On May 7th, 2018 Asier Erramuzpe defended his Thesis titled “Development of new methods for brain connectivity biomarkers in epilepsy and other pathological conditions”. He got ”Cum Laude por Unaminidad”. Zorionak!!
2018, Brain connectivity for quantification of emergence, dysfunction and reorganization of the pathological brain. Seminars organized by the Neurodegenerative Diseases Group at Biocruces. Barakaldo, Spain
2018, La neuroimagen computacional. Una recreación funcional de la neuroanatomia. Ciclo de conferencias FME 50 Urte. Leioa, Spain
In collaboration with Luca Gerardo – Giorda (BCAM, Bilbao) and Sebastiano Stramaglia (Univ of Bari), we are organizing the 2018 Quantitative Biomedicine Workshop. Further information (program and registration info) can be found at http://www.bcamath.org/en/workshops/qbio2018 The poster conference [pdf] The book of abstracts [pdf]
T. Lissek., et. al. , M.T. Hasan. Building Bridges through Science. Neuron 96:730-735, 2017 [pdf] Science is ideally suited to connect people from different cultures and thereby foster mutual understanding. To promote international life science collaboration, we have launched ‘‘The Science Bridge’’ initiative. Our current project focuses on partnership between Western and Middle Eastern neuroscience communities.
I am Ikerbasque Research Professor (hosted by the new created BioCruces) Further information: 1. Visit its website 2. Watch this introductory video 3. Read this dossier 4. Watch the video on the 2014 scientific output 5. Read the research strategy for the years 2018-2021 Annual Reports: 1. 2007-2011 scientific output 2. 2012 scientific output 3. 2013 scientific output 4. 2014 scientific output 5. 2015 scientific output 6. 2017 scientific output […]